Statistical, Computational, Translational, and Ethical Challenges in Biobank Data Analysis

Videos from BIRS Workshop

, UCSF
- 09:36
Biobanks from an epidemiologic perspective: experience at Kaiser Permanente
Watch video | Download video: 202407220904-Risch.mp4 (138M)
, Yale University
- 10:07
Organizing Large Consortium Studies Across Diverse Institutions
Watch video | Download video: 202407220937-Ohno-Machado.mp4 (148M)
, Yale University
- 10:40
Natural language processing for unlocking phenotypic information in clinical notes
Watch video | Download video: 202407221019-Xu.mp4 (65M)
, Cedars Sinai Medical Center
- 11:03
Leveraging Biobank-Linked EHR for Genetics Research
Watch video | Download video: 202407221041-Li.mp4 (69M)
, U Penn
- 11:27
Groundwork for Precision Medicine: The Role of Electronic Health Records in Discoveries and Clinical Implementation
Watch video | Download video: 202407221104-Verma.mp4 (81M)
, Massachusetts General Hospital & Broad Institute
- 14:23
All of Us diversity and scale improve polygenic prediction contextually with greatest improvements for under-represented populations
Watch video | Download video: 202407221359-Martin.mp4 (91M)
, The Hong Kong University of Science and Technology
- 15:25
XMAP: Cross-population fine-mapping by leveraging genetic diversity and accounting for confounding bias
Watch video | Download video: 202407221506-Yang.mp4 (55M)
, The Hospital for Sick Children
- 15:48
Everything you always wanted to know about sex chromosomes* (*but were afraid to ask)
Watch video | Download video: 202407221526-Paterson.mp4 (70M)
, Harvard University
- 16:06
Connecting ocular and systemic health: Phenome- and genome- wide analyses of retinal layer thicknesses from optical coherence tomography imaging
Watch video | Download video: 202407221548-Zekavat.mp4 (56M)
, Johns Hopkins University
- 09:30
Integrated Analysis of Biobanks with Summary Statistics
Watch video | Download video: 202407230901-Chatterjee.mp4 (124M)
, National Cancer Institute
- 10:04
Making epidemiology FAIR: retrofitting legacy studies and building new cohorts
Watch video | Download video: 202407230939-Kraft.mp4 (84M)
, UCLA
- 10:44
Scalable mixed models for biobank-scale data: the unreasonable effectiveness of random projections
Watch video | Download video: 202407231023-Sankararaman.mp4 (48M)
, McGill University
- 11:05
Novel Approaches to Exploit Family History in Genetic Association Tests, with Applications to the UK Biobank
Watch video | Download video: 202407231045-Dupuis.mp4 (29M)
, Columbia University
- 11:15
Quantile Regression for biomarkers in the UK Biobank
Watch video | Download video: 202407231055-Ionita-Laza.mp4 (70M)
, National Cancer Institute
- 11:36
Discussion
Watch video | Download video: 202407231113-Kraft.mp4 (73M)
, University of Michigan
- 14:07
VINTAGE: A unified framework integrating gene expression mapping studies with genome-wide association studies for detecting and deciphering gene-trait associations
Watch video | Download video: 202407231346-Zhou.mp4 (52M)
, Penn State University
- 14:27
Integrating single cell eQTLs to dissect risk genes for immune mediated diseases
Watch video | Download video: 202407231407-Liu.mp4 (27M)
, Columbia University
- 14:50
Elucidating Genetic Etiology of Complex Disease through Population-Scale Functional Genomic Studies
Watch video | Download video: 202407231427-Wang.mp4 (64M)
, University of Chicago
- 15:30
Error in prediction does not inflate type I error in TWAS but polygenicity does
Watch video | Download video: 202407231507-Im.mp4 (72M)
, University of Minnesota
- 15:53
Enhancing non-linear TWAS/PWAS via trait imputation with applications to Alzheimer's disease
Watch video | Download video: 202407231531-Pan.mp4 (74M)
, University of Michigan
- 16:18
Discussion
Watch video | Download video: 202407231553-Zhou.mp4 (44M)
, Westlake University
- 09:27
Genetics and clinical implications of somatic mutational burden in normal blood
Watch video | Download video: 202407240900-Yang.mp4 (34M)
, The University of North Carolina at Chapel Hill
- 09:48
Genetic Architecture of Brain and Heart
Watch video | Download video: 202407240928-Zhu.mp4 (37M)
, Stanford University
- 10:35
Ethical Implications of Biobank Analysis: From humans, to data, and back again
Watch video | Download video: 202407241016-Martschenko.mp4 (32M)
, Brigham and Women's Hospital and Harvard Medical School
- 10:53
Data governance strategies for minimizing risks from reidentification and group harms
Watch video | Download video: 202407241034-Lewis.mp4 (62M)
, Columbia University
- 11:24
Computationally Efficient Approaches for Whole-Genome Quantile Inference with Related Samples
Watch video | Download video: 202407241101-Wang.mp4 (63M)
, University of Leicester
- 09:20
GWAS and Mendelian randomisation of disease progression traits
Watch video | Download video: 202407250900-Dudbridge.mp4 (28M)
, University of Cambridge
- 09:40
Some recent progress in Mendelian randomization
Watch video | Download video: 202407250920-Zhao.mp4 (25M)
, Case Western Serve University
- 10:04
Uncovering Gene-Environment Interactions through Mendelian Randomization
Watch video | Download video: 202407250941-Zhu.mp4 (69M)
, University of Wisconsin-Madison
- 10:44
Challenges in causal interpretation of Mendelian Randomization with large biobank data
Watch video | Download video: 202407251024-Lu.mp4 (71M)
, University of Toronto
- 11:14
Fighting Noise with Noise: Mendelian Randomization Studies with Pseudo Variables
Watch video | Download video: 202407251052-Kong.mp4 (72M)
, McGill University
- 11:37
Multi-ancestry proteome-wide Mendelian randomization offers a comprehensive protein-disease atlas and potential therapeutic targets
Watch video | Download video: 202407251114-Su.mp4 (87M)
, Case Western Serve University
- 12:03
Discussion
Watch video | Download video: 202407251137-Zhu.mp4 (103M)
, The University of Sydney
- 14:09
Exploring genomic influence on in-silico spatial gene expression data
Watch video | Download video: 202407251349-Yang.mp4 (63M)
, Microsoft Research
- 14:31
Discovering non-additive heritability using additive GWAS summary statistics
Watch video | Download video: 202407251409-Crawford.mp4 (64M)
, Montreal Heart Institute
- 14:49
Improving understanding of complex trait genetics with probabilistic graphical models and variational inference
Watch video | Download video: 202407251431-Zhang.mp4 (57M)
, Fred Hutchinson Cancer Center
- 15:28
Evaluating the performance of Polygenic Risk Scores in Diverse Populations
Watch video | Download video: 202407251505-Kooperberg.mp4 (53M)
, University of North Carolina
- 15:49
Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-differential effects via GAUDI
Watch video | Download video: 202407251528-Li.mp4 (54M)
, U Toronto
- 16:11
Detecting latent gene-environment interaction when analyzing binary traits
Watch video | Download video: 202407251550-Zhang.mp4 (69M)
, Microsoft Research
- 16:32
Discussion
Watch video | Download video: 202407251611-Crawford.mp4 (53M)
, McGill University
- 09:06
Statistical, Computational, Translational, and Ethical Challenges in Biobank Data Analysis: a Neuroimaging Perspective
Watch video | Download video: 202407260852-McPherson.mp4 (39M)
, Université de Montréal
- 09:32
How to assess risks to privacy and confidentiality in multi-omic research and databases
Watch video | Download video: 202407260910-Dupras.mp4 (47M)
, McGill University
- 09:56
DKLasso: Deep Kernel Learning for Robust Prediction and Feature Selection — Applications to the CLSA Biobank for Exploring Metabolite-Epigenetic Aging Associations
Watch video | Download video: 202407260933-Zeng.mp4 (50M)